Hepatic Lipid Accumulation Alters Global Histone H3 Lysine 9 and 4 Trimethylation in the Peroxisome Proliferator-Activated Receptor Alpha Network (original) (raw)
Figure 3
Effect of H3K4me3 and H3K9me3 on the PPARĪ±-network in lipid-accumulated mouse primary hepatocytes.
Lipid metabolism-associated H3K9me3 and H3K4me3 targets (p<0.05) were selected based on Gene Ontology annotation, and their biological relationship was analyzed using the PubGene database. Red indicates H3K9me3 and H3K4me3 targets detected by ChIP-on-chip analysis and dark red represents those genes possessing a potential biological relationship with targets detected by ChIP-on-chip analysis based on previous reports.