Progression of Cartilage Degradation, Bone Resorption and Pain in Rat Temporomandibular Joint Osteoarthritis Induced by Injection of Iodoacetate (original) (raw)
Figure 1
Outline of experimental design and confirmation of injection site into upper compartment of rat TMJ.
A: Outline of experimental design. B: Photograph of dye (fast green solution) injection into the upper compartment of the left TMJ. (a). Needle insertion was 5 mm anterior to the external auditory canal. (b). Dissection showed that the needle was right under the root of the zygoma (dotted arrow), anterior of the external auditory canal (arrow), stopped at the temporal fossa, and was located in the upper compartment (black circle). (c). 50 µL dye was injected. (d). Opening the capsule revealed that the dye was restricted to the upper compartment of the TMJ (disc and condyle: hollow arrow).