Adipocyte Dysfunction in a Mouse Model of Polycystic Ovary Syndrome (PCOS): Evidence of Adipocyte Hypertrophy and Tissue-Specific Inflammation (original) (raw)
Figure 5
IR/LepRPOMC females are hyperglycemic and show hyperglycemia during pregnancy.
A. IR/LepRPOMC female glucose levels under basal conditions (n = 6–7) ** p<0.01. B. Fasted glucose levels in a second cohort of females, before pregnancy and on gestational day 12 and 15 (Black circles are control dams, open triangles are IR/LepRPOMC dams; n = 11–12) * p<0.05, compared with controls at same timepoint; + p<0.05, compared with pre-pregnancy values of same group. C. Glucose tolerance testing (2 g/kg) performed on day 15–18 of gestation. (Black circles are control dams, open triangles are IR/LepRPOMC dams; n = 6). Mean ± SEM.