FGF21 Requires βklotho to Act In Vivo (original) (raw)
Figure 1
Expression of FGFR/Klotho receptor components (A–F), KLB protein expression in liver and WAT (G).
Induction of immediate early genes EGR-1 (H) and cFOS (I) expression in WAT of WT and KLBKO animals following acute FGF21 treatment. Statistical analysis was performed using one-way ANOVA, followed by Dunnett’s multiple comparisons test where appropriate. Differences were considered significant when P≤0.05.