Genome-Wide Association Study of Retinopathy in Individuals without Diabetes (original) (raw)
Figure 1
Regional association plot of SNP rs12155400 on chromosome 7 for Caucasians.
This figure is the regional association plot of SNP rs12155400 on chromosome 7 that reached genome-wide significance in the meta-analysis of GWAS results in participants of European ancestry without diabetes or hypertension. The lead and surrounding SNPs are color coded according to the pair-wise linkage disequilibrium (LD) with the lead SNP (presented as a diamond) on a scale of r2 from 0 to 1. Estimated recombination rates reflect the local LD structure in the 500 kb buffer around the index SNP and plotted based on values from HapMap II Centre d’Etude du Polymorphisme Humain collection samples from a Utah (CEU) population.