Retinal Adaptation to Changing Glycemic Levels in a Rat Model of Type 2 Diabetes (original) (raw)
Figure 5
Retinal morphology.
Hematoxylin and eosin stainings are shown for cryostat sections obtained from 31-week-old Lean (a) and ZDF (b) rats and from untreated (c) and insulin treated (d) ZDF rats at 23 weeks of age. The average number+SD of cell rows (e) in ONL and INL at 23 weeks of age were calculated for Lean (n = 4), untreated ZDF (n = 3) and insulin-treated ZDF (n = 6) rats, and no significant differences were detected (one way ANOVA; p>0.05). ZDF-i, insulin-treated ZDFs; ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer; IPL, inner plexiform layer; GCL, ganglion cell layer. Scale bar = 10 µm.