Acute Colitis Induces Neurokinin 1 Receptor Internalization in the Rat Lumbosacral Spinal Cord (original) (raw)
Figure 4
The Fos immunoreactive (Fos-ir) neurons mainly distributed in DCN in the spinal cord (A).
*P<0.01 DCN vs. SDH or IML. The number of Fos-ir DCN neurons showed that in the formalin instillation group (“For”, ▪), Fos begin to increase 15 min after irritation and peaked at 60 min, then returned to normal compared to the saline instillation group (“Sal”, •) and naïve group (“Nai”, ▴) 3 h later (B). **P<0.001 formalin instillation vs. saline instillation or naive group. n = 6 in each group. Values are means ± S.E.M.