Sex Bias in Experimental Immune-Mediated, Drug-Induced Liver Injury in BALB/c Mice: Suggested Roles for Tregs, Estrogen, and IL-6 (original) (raw)
Figure 8
IL-6 supplementation diminishes Tregs in TFA-S100 – immunized male and female splenocyte cultures in vitro.
IL-6 supplementation (25 ng/mL) of in vitro splenocyte cultures from female (A) and male (B) TFA-S100-immunized BALB/c mice diminished Tregs in both groups. (Experiments run in duplicate, n = 3 mice/group, Mann-Whitney U, * = p<0.05, ** = p<0.01, *** = p<0.001).