A Protein Prioritization Approach Tailored for the FA/BRCA Pathway (original) (raw)
Figure 5
Distribution of haploinsufficiency probabilities (p(HI)).
Distribution of haploinsufficiency probabilities (p(HI)) for the human genome (from Huang et al. [61]). The mean p(HI) values for all human genes and 143 genes of our top 150 set are given as respectively, light blue and orange circles on the x-axis. p(HI) = 1 means highly haploinsufficient, p(HI) = 0 haplosufficient.