Age-Mediated Transcriptomic Changes in Adult Mouse Substantia Nigra (original) (raw)
Figure 3
Validation of microarray results in SNpc by real time quantitative PCR.
Relative log2 fold changes of mRNA were presented comparing late middle-aged (18months old) to young (2month old) mice. Positive numbers corresponded to up-regulated genes, whereas negative numbers indicated down-regulated genes. *, p<0.05 comparing 18 to 2 months old mice using Student’s _t_-test. n = 4 replicates for each age group.