Correcting for Population Structure and Kinship Using the Linear Mixed Model: Theory and Extensions (original) (raw)
Figure 4
Comparison of eigen-spectra due to population structure and kinship.
The eigen-spectrum based on the known pedigree from 3063 individuals from the Framingham Heart Study reflects kinship, while the eigen-spectrum for four populations from the Multi-Ethnic Study of Atherosclerosis (MESA) reflects both population structure and kinship. Eigen-values for each dataset are normalized by the maximum eigen-value so that each spectrum has a maximum of 1.