Defining the Vulnerable Period for Re-Establishment of Clostridium difficile Colonization after Treatment of C. difficile Infection with Oral Vancomycin or Metronidazole (original) (raw)
Figure 4
Relative abundance of bacterial phyla in stool of 8 patients treated with oral vancomycin.
Stool specimens collected before or after completion of vancomycin therapy for Clostridium difficile infection (CDI), stratified by those with intact (i.e., C. difficile growth suppressed) or disrupted (i.e., C. difficile growth supported) colonization resistance based on the in vitro colonization assay. Micriobiota of each stool specimen was evaluated by deep 16S rRNA sequencing. Each column represents total phyla distribution of one sample. Columns are labelled with sample ID and timing of stool collection in comparison to vancomycin treatment.