Tissue Distribution of Berberine and Its Metabolites after Oral Administration in Rats (original) (raw)

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Figure 2

Tissue distribution of BBR.

2A Plasma concentration-time profile of BBR after oral administration of 200 mg/kg in 48 h (n = 6) 2B Profiles of BBR in liver distribution in SD rats after oral administration of 200 mg/kg (n = 6) 2C Profiles of BBR in kidney distribution in SD rats after oral administration of 200 mg/kg (n = 6) 2D Profiles of BBR in muscle distribution in SD rats after oral administration of 200 mg/kg (n = 6) 2E Profiles of BBR in lung distribution in SD rats after oral administration of 200 mg/kg (n = 6) 2F Profiles of BBR in brain distribution in SD rats after oral administration of 200 mg/kg (n = 6) 2G Profiles of BBR in heart distribution in SD rats after oral administration of 200 mg/kg (n = 6) 2H Profiles of BBR in pancreas distribution in SD rats after oral administration of 200 mg/kg (n = 6) 2I Profiles of BBR in fat distribution in SD rats after oral administration of 200 mg/kg (n = 6).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0077969.g002