Local IL-17A Potentiates Early Neutrophil Recruitment to the Respiratory Tract during Severe RSV Infection (original) (raw)
Figure 2
IL-17A and RSV synergistically induce IL-8 production by airway epithelial cells.
A549 airway epithelial cells were infected with RSV or UV-inactivated RSV for 24 hours at a multiplicity of infection of 3 and in the presence of IL-17A. (A) IL-8 mRNA levels measured by qPCR. Data represents 3-4 experiments. (B) Concentration of IL-8 in the supernatant of RSV-infected and IL-17A treated A549 cells. Data represents 3-5 experiments. * denote significance of p<0.05, **** denote significance of p<0.0001.