Combined miRNA and mRNA Signature Identifies Key Molecular Players and Pathways Involved in Chikungunya Virus Infection in Human Cells (original) (raw)

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Figure 5

CHIKV regulates TGF-β, Endocytosis and Cell Cycle pathway genes.

(A) qRT-PCR based validation of differential expression of genes belonging to TGF-β, endocytosis and cell cycle pathways in response to CHIKV infection in HEK293T cells and (B) human dermal fibroblasts (C) Effect of TGF-β receptor inhibitor on the progression of CHIKV infection in HEK293T cells. The graphical data points represent mean+S.D of at least three independent experiments. (*P<0.05, **P<0.01). Error bars denote + SD.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0079886.g005