Functionally Enigmatic Genes: A Case Study of the Brain Ignorome (original) (raw)
Figure 2
Expression comparison between a few well-studied and ignorome genes in multiple tissues and organs.
The x-axis represents multiple tissues and organs including several brain regions represented by red colored bars. y-axis represents the log2 transformed expression values downloaded from BioGPS (www.biogps.org). We included interesting examples including (1) GAPDH, a house keeping gene, (2) MBP, an extensively studied gene with high brain selectivity, (3) HTT (HD), an important neuroscience gene with low brain selectivity, and ignorome genes including FAM155A, C16orf15, VSTM2A, and LONRF2 with highly selective expression in brain.