Adrenergic β2-Receptors Mediates Visceral Hypersensitivity Induced by Heterotypic Intermittent Stress in Rats (original) (raw)
Figure 7
Incubation of NE increased number of AP evoked by ramp current stimulation.
(A) Representative traces of APs induced by a ramp current injection (left, 100 pA; middle, 300 pA; right, 500 pA) before (Pre) and after (Post) NE application. (B) Bar graph showed a significant increase in the number of APs in response to ramp stimulations after NE application, *p<0.05 **p<0.01 vs. pre-NE. (C, D, E) Time to first peak (TTFP) of AP in response to 100 pA (C, *p<0.05, compared with Pre), 300 pA (D,*p <0.05, compared with Pre) and 500 pA ramp current stimulation (E, *p<0.05, compared with Pre) was significantly decreased after NE incubation.