γδ T Cells Are Required for Pulmonary IL-17A Expression after Ozone Exposure in Mice: Role of TNFα (original) (raw)
Figure 4
Impact of TNFR2 deficiency (A–C) or etanercept (D–F) on O3-induced inflammation in obese (Cpefat) and lean (WT) mice.
(A, D) BAL neutrophils; (B, E) Il17a mRNA expression; (C, F) BAL G-CSF. Results are mean±SE of data from 3–11 mice in each group.*p<0.05 versus air-exposed mice of same genotype and treatment; #p<0.05 versus exposure matched lean mice with same TNFR2 genotype or treatment; & p<0.05 versus TNFR2 sufficient (A–C) or vehicle treated mice (D–F) with same exposure and Cpe genotype.