γδ T Cells Are Required for Pulmonary IL-17A Expression after Ozone Exposure in Mice: Role of TNFα (original) (raw)
Figure 6
TNFα signaling is required for expression of Il12Rβ1 and Ccl20.
(A) BAL IL-6; (B–D)) Il23 (p19) mRNA; (E–G) Ccl20 mRNA; (H) Il12Rβ1 mRNA; (I) MFI and (J) % of γδ T cells positive for IL-12Rβ1 after stimulation with TNFα Results are mean±SE of data from 3–11 mice in each group. *p<0.05 versus air exposed mice of the same genotype; #p<0.05 versus exposure matched lean mice with the same TNFR2 genotype or treatment; & p<0.05 versus WT; %<0.05 obese versus lean regardless of TNFR2 genotype.