Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages (original) (raw)
Figure 1
Human macrophages and dendritic cells express human 12-LOX.
(A) Expression levels of 12-LOX mRNA in human monocytes (MC), M0, M1, M2 macrophages, immature dendritic cells (iDC) and mature dendritic cells (mDC) were assessed by quantitative PCR. (B) 12-LOX protein expression levels were assessed by flow cytometry. In the left panel, a representative histogram shows 12-LOX present in each cell type. In the right panel, results are mean fluorescent intensity (MFI) of 12-LOX protein levels for each cell type, expressed as mean±SEM of 4 separate cell preparations (*P<0.05, **P<0.01).