Investigation of 6-[18F]-Fluoromaltose as a Novel PET Tracer for Imaging Bacterial Infection (original) (raw)
Figure 1
In vitro characterization of 6-[18F]-fluoromaltose.
A) Uptake of 6-[18F]-fluoromaltose in the indicated strains of bacteria for 60 minutes. B) 1 hour uptake of 6-[18F]-fluoromaltose in the mammalian cell lines, MDA MB231 and HeLa and its uptake in E.coli in the presence of 1 mM maltose. C) Bioluminescence imaging of a macrophage cell line J774 infected with a bioluminescent strain of Listeria monocytogenes. D) 1 hour uptake of 6-[18F]-fluoromaltose in the bioluminescent strain of Listeria monocytogenes and in macrophage cell line J774 with and without intracellular Listeria infections.