γδT Cells Are Prevalent in the Proximal Aorta and Drive Nascent Atherosclerotic Lesion Progression and Neutrophilia in Hypercholesterolemic Mice (original) (raw)
Figure 2
γδT cells are the dominant T cell subset in early lesions and associated adventitia of ApoE KO mice.
En face confocal images of aortic tissue from Western diet-fed ApoE KO mice stained with anti-CD3-FITC (green), anti-TCRγδ APC (red), and DAPI (blue). γδT cells constitute the majority of CD3+ T cells in aortic root intima (A) and adventitia (B). γδT cells infiltrate the adventitia at intercostal artery branch points of the descending thoracic aorta (C). White scale bar = 10 µm. D: Quantitation: n = 3.