Mycobacterium abscessus Morphotype Comparison in a Murine Model (original) (raw)
Fig 4
Weight trends.
(A and B) Mice inoculated with M. abscessus trended towards greater weight loss than mice inoculated with sterile thrombin/ fibrinogen. (N = 19–40 mice in each M. abscessus group, N = 6–16 mice in each sterile inoculum group). Mice receiving smooth morphotype inoculation that had some colony conversion to rough morphotype on either BALF, lung, or spleen cultures had trend towards greater weight loss and slower weight gain. (N = 8–10 for WT mice, 4–6 for CF mice). Data displayed as mean of group, pooled from 2–3 replicate experiments for each morphotype.