Binding of Subdomains 1/2 of PfEMP1-DBL1α to Heparan Sulfate or Heparin Mediates Plasmodium falciparum Rosetting (original) (raw)
Fig 5
RBC and receptor binding site of NTS-DBL1α IT4var60.
A) Molecular model of NTS-DBL1α IT4var60 showing the residues involved in RBC binding (Y73, K97 and K263), rosette inhibition (Y73 and K263) and heparin binding (K97). B) Comparison with previously identified residues that are important for BgA binding to the PAvarO variant (K179, K95, K166, R69: purple) [21].