Preservation of the Blood Brain Barrier and Cortical Neuronal Tissue by Liraglutide, a Long Acting Glucagon-Like-1 Analogue, after Experimental Traumatic Brain Injury (original) (raw)
Fig 5
Evans blue exudation.
A: Analysis of Evans Blue extravasation (μg/mg of dry brain tissue) 48 hours after CCI in rats. Treatment with Liraglutide 200 μg/kg BID significantly reduced Evans Blue extravasation in both hemispheres. B: Illustration of coronal sections through the contusion center illustrates Evans blue distribution throughout the rat brain. Evans blue extravasation is particularly prominent in the pericontusional cortex, hippocampus and upper thalamus. Values are mean ± SEM. *:p<0.05.