A Deletion in FOXN1 Is Associated with a Syndrome Characterized by Congenital Hypotrichosis and Short Life Expectancy in Birman Cats (original) (raw)
Fig 3
Wild type and mutant FOXN1 proteins.
Alignment of partial amino acids sequences of FOXN1, translated from the wild type alleles reported in human (Homo, ENSP00000226247), mouse (Mus, ENSMUSP00000103929), cat [Felis (WT), ENSFCAP00000007665] and the c.[1030_1033delCTGT] mutated allele identified in hairless Birman cats (hairless). Amino acids encoded by exons 1 to 5 are omitted and alignment start with amino acid number 310 in human and mouse proteins, or amino acid number 309 in the feline protein. Human FOXN1 sequence was used as the reference sequence. Dashes represent identical amino acids compared to the reference sequence. FOXN1 structural features were depicted according to [26–29].