PKM2 Subcellular Localization Is Involved in Oxaliplatin Resistance Acquisition in HT29 Human Colorectal Cancer Cell Lines (original) (raw)
Fig 7
BMF is involved in oxaliplatin response and cell death at the transcriptional level A.
Changes in BMF gene expression between OXA treated (T) and non-treated (NT) HT29, siPKM2- HT29 and HTOXAR3 cells. Vertical bars in the graphics represent means obtained from at least 3 independent experiments ± SD. B. Percentage of dead cells after treatment with oxaliplatin and/or BMF gene knockdown. Bars represent means obtained from at least 3 independent experiments ± SD. The Little graph shows percentage (mean ± SD) of BMF expression inhibition after siRNA transfections. * P- value < 0.05. ** P-value < 0.01; *** P-value < 0.001