Molecular Dynamics Simulations of the Human Glucose Transporter GLUT1 (original) (raw)
Fig 2
Comparison of interactions between TM domains and intracellular helices (ICH) domain of GLUT1.
(A) the opened inward-facing (X-ray structure). (B) the opened outward-facing conformation (the result of the CMD simulation). The N-terminal TM domain, C-terminal TM domain, and ICH domain are shown in cyan, orange, and green, respectively. The possible hydrogen bonds and the corresponding residues are described as dashed black lines and sticks, respectively.