The CAF-1 and Hir Histone Chaperones Associate with Sites of Meiotic Double-Strand Breaks in Budding Yeast (original) (raw)
Fig 4
The Hir histone chaperone is recruited to meiotic DSB.
(A) Hir1-3HA association with the VDE DSB site and one Spo11 DSB site (GAT1) relative to the negative control site. ChIP from VBD1292 (VRS::ARE1/VRS mut::ARE1) and from VBD1322 (VRS mut::ARE1/VRS mut::ARE1) meiotic time course. (B) Hir1-3HA association as in A from a dmc1Δ VRS::ARE1/VRS mut::ARE1 time-course (VBD1312).