Mouse Models of Diet-Induced Nonalcoholic Steatohepatitis Reproduce the Heterogeneity of the Human Disease (original) (raw)
Fig 1
Effects of MCD diet and Western diet on metabolic profile.
WT mice were fed chow diet, MCD diet for 8 weeks, or Western diet for 16 weeks, and sacrificed at 20 weeks of age. (A). Body weights; (B). Adipokines (leptin and adiponectin); (C). Fasting serum glucose and HOMA-IR index; (D). Serum triglycerides and non-esterified fatty acids (NEFA’s). Mean±SEM results are graphed. *<0.05 and **<0.005, control versus experimental diet; #<0.05 and ##<0.005, MCD versus Western diet.