Cervical Microbiome and Cytokine Profile at Various Stages of Cervical Cancer: A Pilot Study (original) (raw)
Fig 4
Beta-diversity of microbial communities by histopathological diagnosis.
A. PCoA profile of the histopathological diagnosis displayed with weighted UniFrac distances. Each figure represents one sample colored according to its histopathological diagnosis. Red circles represent HPV-negative NCL samples; blue squares represent HPV-positive NCL samples; orange triangles represent SIL and green triangles represent CC. A1. Principal component (PC)-1 accounted for 33.44% of the variation in the composition of the microbiota due to the presence of Sneathia spp. and Fusobacterium spp. A2. PC-2 accounted for 26.85% of the variation inthe composition of the microbiota due to the presence of Bifidobacteria spp. and Pseudomonas spp. A3. PC-3 accounted for 10.38% of the variation in the composition of the microbiota due to the presence of Lactobacillus spp. and Streptococcus spp. B. B1. Variation of weighted UniFrac distances within each histological diagnosis group. B2. Variation of weighted UniFrac distances compared with -HPV-negativeNCL.