Identification of Host Insulin Binding Sites on Schistosoma japonicum Insulin Receptors (original) (raw)
Fig 1
Schematic model of the SjIRs with approximate locations of mapped peptide analogues 1-22.
Peptides 1-10 (in red) are located on SjIR-1; peptides 11, 13-22 (in blue) are located on SjIR-2. Peptide 9 is located on the HIR (its approximate location relative to the sequence in the SjIRs is indicated). Peptide 12 is the reverse analogue of peptide 9. L1, L1 subdomain; L2, L2 subdomain; CR, cysteine rich domain; FnIII-1-3, fibronectin domains 1, 2 and 3; TM, transmembrane domain; TK, tyrosine kinase domain.