Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4+ T Cell Responses (original) (raw)
Fig 6
Similar levels of TT-specific CD4+ memory T cells after boosting as detected by the AIM assay.
CD25+OX40+ expression by CD4+ memory T cells after 24 hours of culture for donors originally primed with DTwP vaccine not boosted (no boost) or 0.5–6 months post Tdap boost (boost) after TT-megapool (A) or TT (B) stimulation. Each dot represents one donor. Median ± interquartile range is shown. ns: no significant difference by two-tailed Mann-Whitney test