Internal tissue references for 18Fluorodeoxyglucose vascular inflammation imaging: Implications for cardiovascular risk stratification and clinical trials (original) (raw)
Fig 1
Examples of variation in blood activity and aorta wall FDG uptake.
PET (color) and CT (black/white) axial fusion images just below the aortic arch of three subjects, using identical windowing and leveling of PET SUV according to the look up table (left). Red arrows point to regions where aorta wall activity is expected. The top subject has low TBRBlood with high levels of blood activity in the aorta lumen (green). The middle subject has lower blood activity in the lumen of the aorta, which allows visual contrast of the aorta wall, therefore higher TBRBlood. It is not clear if the difference in TBRBlood between the top two subjects is related to differences in inflammation or due to differences in blood activity. However, compared to a subject with active large vessel vasculitis (bottom), there is clearly abnormal aorta wall activity that can be distinguished from blood activity.