Effect of temperature on fatty acid metabolism in skeletal muscle mitochondria of untrained and endurance-trained rats (original) (raw)
Fig 1
The influence of endurance training on mitochondrial oxidation of palmitoylcarnitine (A) and glycerol-3-phosphate (B) at 25°C, 35°C and 42°C. Respiratory rates were measured in mitochondria isolated from control (c) and trained (t) rats in the presence of 150 μM ADP (state 3, phosphorylating respiration) with 0.5 mM palmitoyl-DL-carnitine (A) or 5 mM glycerol-3-phosphate (B). Mean values (± SD) for six mitochondria preparations from six different animals from each group (n = 6) are shown. ###P < 0.001, ##P < 0.01, #P < 0.05 vs value obtained at 35°C for a given group of animals, i.e., within control rats or trained rats. ***P < 0.001, **P < 0.01, *P < 0.05 vs. value obtained for control rats for a given assay temperature.