Identification of novel susceptibility loci associated with hepatitis B surface antigen seroclearance in chronic hepatitis B (original) (raw)

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Fig 3

Gene-set enrichment study of the significantly associated SNPs.

The functional enrichment among the flanking genes of identified susceptibility-associated SNPs (P < 5.0×10−4) was estimated by gene ontology and pathway analyses implemented using DAVID and i-GSEA4GWAS softwares, respectively. The significance of the susceptibility-associated SNPs was estimated with a cutoff of P < 5.0×10−4. * _P_-values obtained from the pathway analysis are indicated.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0199094.g003