Expression of Concern: Resveratrol Enhances Antitumor Activity of TRAIL in Prostate Cancer Xenografts through Activation of FOXO Transcription Factor (original) (raw)
Fig 3
Effects of resveratrol and/or TRAIL on the expression of TRAIL-death receptors.
(A), Immunohistochemistry was performed to measure the expressions of TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and treated mice on week 6. Quantification of DR4 and DR5 positive cells are also shown on right panel. (B), Expressions of TRAIL-R1/DR4, TRAIL-R2/DR5 and β-actin in tumor tissues derived on week 6. Western blot analysis was performed to measure the expression of DRs (left panel). Quantification of DR4 and DR5 positive tumor cells (right panel). (C), Measurement of DR4 and DR5 by ELISA. Proteins extracts were prepared and the expressions of DRs were measured as per manufacturer's instructions.