Ancient Origin and Gene Mosaicism of the Progenitor of Mycobacterium tuberculosis (original) (raw)
Figure 3
Nucleotide Polymorphism Detected in the Six Housekeeping Genes for the 17 Sequenced Strains
(A) Location of the genes on the genome of M. tuberculosis H37Rv. Note that gyrB and gyrA are adjacent.
(B) Pattern of polymorphic sites revealing mosaicism of sequences. Colored blocks correspond to sequence stretches in the smooth strains that are similar or identical to the sequences in the MTBC. Boxes correspond to blocks of consecutive nucleotides in smooth strains that differ by at least three nucleotides from M. tuberculosis H37Rv. The last column indicates the allele number for each gene. Letters N and s indicate nonsynonymous and synonymous substitutions, respectively.