The Beta-Glucan Receptor Dectin-1 Recognizes Specific Morphologies of Aspergillus fumigatus (original) (raw)
Figure 3
Cytokine and Chemokine Induction in Response to Different Heat-Killed Morphologies of A. fumigatus
A. fumigatus was grown for 3 h (in 10% or 20% serum), 6 h, or 9 h and thereafter subjected to heat-killing. Alveolar macrophages were added and incubated in the presence or absence of isotype or 2A11 for 6 h. Thereafter, cytokine and chemokine levels were determined in supernatants by Bio-Plex or ELISA. Asterisks represent significant differences between isotype (rat IgG) and 2A11 (p < 0.05). Figure 3 shows cumulative results from three experiments. Data are expressed as mean pg/ml + SEM.