Retroviral DNA Integration: Viral and Cellular Determinants of Target-Site Selection (original) (raw)
Figure 4
Diagram of the Relationship of Transcription-Factor Binding Sites Enriched in the MLVPuro, MLV-Burgess, HIVmIN, and HIVmGagmIN Integration-Site Datasets
The genomic sequences within 1 kb of each integration site were used for analysis. Ten matched random-control integration sites were compared to each experimental integration site. The cut-off value for over-representation was 2.0-fold. All comparisons achieved p ≤ 0.001. The number of enriched transcription-factor binding sites in each dataset is shown with the number of factors unique to each in parentheses. The edge labels show the number of commonly enriched sites between pairs of datasets.