Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages (original) (raw)
Figure 3
The Early Phase of Pyroptosis Induced by Shigella Is Dependent on Ipaf but Not ASC
Caspase-1-deficient (A and D), Ipaf-deficient (B and E), or ASC-deficient BMMs (C and F) were infected with Shigella WT (A–C) or TTSS mutant S325 (D–F). LDH released from infected BMMs were quantified at the indicated time. Error bars represent mean ± SD.