Members of a Large Retroposon Family Are Determinants of Post-Transcriptional Gene Expression in Leishmania (original) (raw)

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Figure 5

Comparison of the Target Site Duplication (TSD) Flanking LmSIDER2 (A), TbSIDER1 (B), and TbSIDER2 (C) Sequences

In the left margin, the name of the element is indicated (the chromosome number is followed by the locus number). In this figure, only the LmSIDER/TbSIDER elements flanked by a TSD presenting two mismatches at the most are shown. The underlined names mean that the corresponding element is flanked by conserved TSD. The alignment of all the selected sequences was based on the retroelement sequences (grey column headed “LmSIDER2/TbSIDER1/TbSIDER2”) from which only the first 10 bp and the last 6 bp are shown (the conserved residues of the retroposon are boldfaced and capital characters). The TSD flanking the retroelements is indicated by boldfaced and underlined capital characters for the conserved residues. Lowercase characters in the TSD column correspond to nonconserved residues. In (A), T residues within the 5′-flanking sequences (called “5′”) that are abundant upstream of the TSD are indicated with white characters on a black background.

Figure 5

doi: https://doi.org/10.1371/journal.ppat.0030136.g005