Commensal-Induced Regulatory T Cells Mediate Protection against Pathogen-Stimulated NF-κB Activation (original) (raw)
Figure 3
NF-κB activation is suppressed in LPS-injected mice when pre-treated with B. infantis.
(A) Whole body imaging of NF-κB_lux_ mice 4 hours following LPS injection reveals suppressed NF-κB activation in the _B. infantis_-fed animals. (B) Organs were removed for imaging purposes and a representative image is illustrated. (C) The mean increase in NF-κB activation following i.p. injection of LPS is significantly less in the ileum, spleen and liver of _B. infantis_-fed mice. *p<0.05 versus placebo, n = 5/group.