MyD88 Is Required for Protection from Lethal Infection with a Mouse-Adapted SARS-CoV (original) (raw)

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Figure 2

Virus replication is sustained and distribution is more widespread within the lungs of MyD88−/− mice as compared to WT mice.

5 µM paraffin-embedded sections derived from the lung tissue of WT and MyD88−/− mice were hybridized with an 35S-UTP-labeled riboprobe complementary to either the N gene of SARS-CoV (Urbani) or to the EBER2 gene from Epstein-Barr virus (data not shown). Images (magnification, 100×) are representative of at least three mice.

Figure 2

doi: https://doi.org/10.1371/journal.ppat.1000240.g002