Quantitative Metabolomics Reveals an Epigenetic Blueprint for Iron Acquisition in Uropathogenic Escherichia coli (original) (raw)
Figure 1
LC-MS metabolite profiling reveals differential product formation based on media iron content.
Depicted are total ion chromatograms of conditioned culture media following 18 hour culture of E. coli strain rUTI2 in M63 media containing 1 µM (“iron poor”, top trace) or 100 µM ferric chloride (“iron rich”, top trace). Mass spectrometric analysis confirms that the majority of differentially expressed peaks in the iron poor supernatant derive from siderophores.