In Vivo Transcriptional Profiling of Listeria monocytogenes and Mutagenesis Identify New Virulence Factors Involved in Infection (original) (raw)
Figure 5
In vivo characterization of new Listeria mutants.
BALB/c mice were intravenously inoculated with 104 CFUs. The number of bacteria in the spleen (A) and liver (B) of mice was determined at 72 h post-infection. A prsA mutant was constructed and used as control. Five mice for each bacterial strain. Statistically significant differences are indicated as compared to wild type strain: ** = P<0.01, *** = P<0.001.