Draft Genome Sequencing of Giardia intestinalis Assemblage B Isolate GS: Is Human Giardiasis Caused by Two Different Species? (original) (raw)
Figure 4
Comparison of encystation-specific promoters.
The promoters of the cyst-wall proteins-1 and 2 (CWP-1 and CWP-2), the encystation-specific transcription factor (gMyb2), the key enzymes involved in the synthesis of cyst wall sugars, glucosamine-6 phosphate isomerase (G6PI-B) and UDP-glucosamine-4 epimerase (UG4E) were aligned using the program CLUSTALW. Poly A rich initiator regions and gMyb2 binding-sites are underlined. Note that the G6PI-B and UG4E promoters are missing the gMyb2 binding-sites, whereas they are found in the corresponding positions in the promoters of CWP-1 and –2 and gMyb2.