Nucleoporin 153 Arrests the Nuclear Import of Hepatitis B Virus Capsids in the Nuclear Basket (original) (raw)

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Figure 8

Scatter plots of the relative intranuclear concentrations of M9- and NLS-BSA in individual cells preloaded with P-rC.

Each point represents one cell. X-axis: Intranuclear concentration of the M9-BSA. Y-axis: Intranuclear concentration of NLS-BSA. Both axes give the relative intranuclear cargo concentration in %. The dotted lines show the regression lines. The corresponding slope is given in each panel. The average number of capsids per NPC is given on top of each panel. A. Negative control at 4°C. B. Positive control without capsid preload. C.–H. Increasing amounts of P-rC as in Figure 8. 100%: mean value of the positive import reaction. Only those cells were analyzed in which the section was within the equatorial region (570 cells total).

Figure 8

doi: https://doi.org/10.1371/journal.ppat.1000741.g008