13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation (original) (raw)

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Figure 10

The GAS pathway.

Schematic of the GAS pathway which is characterised by flux through the glyoxylate shunt and anaplerotic reactions for oxidation of pyruvate and succinyl CoA synthetase for the generation of succinyl CoA. The substrate abbreviations are as in Figure 4.

Figure 10

doi: https://doi.org/10.1371/journal.ppat.1002091.g010