Glycosaminoglycans and Sialylated Glycans Sequentially Facilitate Merkel Cell Polyomavirus Infectious Entry (original) (raw)

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Figure 2

Neuraminidase treatment of A549 cells.

The binding of Alexa Fluor 488-conjugated capsids (top panel) or reporter vector-mediated delivery of a GFP reporter gene (bottom panel) to A549 cells treated with neuraminidase was measured by flow cytometry. Results were standardized to mock-treated A549 cells. The average of three separate experiments is shown and error bars represent the standard deviation. See also Figure S2, which shows unstandaradized raw data for an individual experimental replicate.

Figure 2

doi: https://doi.org/10.1371/journal.ppat.1002161.g002